refractory

 Longman Dictionary of Contemporary English 5++朗文当代英语 5++LDOCE 5++朗文 5++re·frac·to·ry /rɪˈfræktəri/ adjective  1. formalDISOBEY deliberately not obeying someone in authority and being difficult to deal with or control 难驾驭的，不服管教的 SYN unruly2. medical a refractory disease or illness is hard to treat or cure 〔疾病〕难以医治的；难以治愈的

Examples from the Corpus

refractory• The tale of Gormenghast requires a large number of refractory animals, few of them capable of taking direction.• Initial therapy of patients with large tumor masses has been complicated by large releases of intracellular potassium with resultant refractory hyperkalemia.• Monamine oxidase inhibitors are used occasionally in migraine patients who are refractory to other prophylactic drugs.Origin refractory (1600-1700) Latin refractarius, from refragari “to oppose”

re·frac·to·ry adjectiveChineseSyllable  

deliberately Corpus authority in someone not obeying

refractory
re‧frac‧to‧ry /rɪˈfræktəri/ adjective1. formal deliberately not obeying someone in authority and being difficult to deal with or control
   SYN  unruly
2. medical a refractory disease or illness is hard to treat or cure

re·frac·toryBrE /rɪˈfræktəri/ 🔊NAmE /rɪˈfræktəri/ 🔊 adjective(formal) (of a person 人) difficult to control; behaving badly 难以驾驭的；行为乖戾的(medical 医学) (of a disease or medical condition 疾病或身体状况) difficult to treat or cure 难以诊治的；难以治愈的